What Is Zepbound vs Mounjaro? 

If you have type 2 diabetes and wish to keep it under control or wish to shed some weight, your physician may have recommended Mounjaro or Zepbound. The producers of these two drugs are Eli Lilly, and both have tendencies to cause diarrhea, nausea, and vomiting; their active component is tirzepatide. Let’s discuss in detail: What is Zepbound vs Mounjaro? 

Key Difference Between Zepbound and Mounjaro 

In the UK, the medicine goes by the name “Mounjaro” and is useful in diabetes and the management of Obesity. However, in the US, the same compound is marketed as ‘’Zepbound” for managing obesity and ‘’Mounjaro” for type 2 diabetes.  

The generic names of tirzepatide include Zepbound and Mounjaro. This is aimed at the glucagon-like peptide-1, GLP-1, a hormone branded in the dual role of a glucose and hunger regulator. These medications function in this way: they resemble GLP-1, and they regulate blood sugar, hunger, and feeding, which causes diabetic people to lose weight. Tirzepatide is marketed in the US as well as in other parts of the world for weight loss under the name “Zepbound” and for diabetes treatment as “Mounjaro.”  

The FDA has authorized Zepbound and Mounjaro to treat different medical conditions; Zepbound addresses weight loss, while Mounjaro cures type 2 diabetes. Continue reading to learn the meaning of What is Zepbound vs Mounjaro? their differences and similarities. 
 

Active Ingredients 

The active component of Zepbound and Mounjaro is tirzepatide. Tirzepatide’s physiological effects are imitated by two endogenous hormones: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1).  

GLP-1 slows down digestion by making food move from your stomach to your intestine more slowly after you eat, a process known as gastric emptying. Simultaneously, it increases insulin release and decreases glucagon release. GIP amplifies these effects of glucagon inhibition and insulin stimulation, improving fat burning in your body. These two actions work together to help reduce blood sugar levels and make you feel fuller sooner. You could eat less as a result and shed some pounds. 

More research suggests that GLP-1 and GIP have an impact on your brain, which may influence your appetite and feel full. When Mounjaro initially came on the market, it was the first medication of its kind to target both GIP and GLP receptors. This sets it apart from other injectable drugs for weight reduction or type 2 diabetes, including Wegovy or Ozempic, which exclusively target the GLP-1 receptor.  

Side Effects 

The list of gastrointestinal side effects for Zepbound and Mounjaro is comparable and often falls into the mild to severe category. Typical adverse effects include: 

• Nausea 

• Diarrhea 

• Decreased appetite 

• Vomiting 

• Constipation 

• Indigestion or an upset stomach 

• Stomach pain 

Other potential side effects of Zepbound include injection site reactions (bruising, redness, or irritation at the injection site), fatigue, allergic reactions (typically rash and itching), belching, hair loss, and acid reflux. 

Overcome Effects of Zepbound or Mounjaro 

Thus, if it is appropriate, your healthcare provider will allow you to consume either Zepbound or Mounjaro after considering your family’s medical history and a list of prescription drugs and vitamin supplements you take. The usual digestive adverse effects of these medications may be lessened by taking them as per directions. Likewise, dietary modifications like: 

• Consuming a lot of nutritious drinks. 
• Consuming bland meals like bread, crackers, or rice, or items that are easy to digest 
• Steer clear of alcohol, fried meals, spices, and fatty foods. 
• Eat smaller meals more frequently than large meals. 
  
  

Which Works Better: Zepbound or Mounjaro?  

Zepbound and Mounzaro can be very helpful for people with type 2 diabetes, obesity, or overweight when used together. After about a year and a half, individuals with obesity who were not diabetic lost an average of 15% to 21% of their body weight. In addition to losing weight, the participants saw noteworthy improvements in other aspects of their cardiometabolic health, including: 

• Reduced waist circumference. 

• Lower blood pressure. 

• Lower cholesterol. 

• Enhanced physical capabilities. 

Moreover, almost 95% of patients who started the trial with prediabetes achieved normal blood sugar levels by the end of the investigation. 

In a type 2 diabetes clinical trial, Mounjaro reduced hemoglobin A1c (HbA1c) levels on average by 1.87% to 2.07%. Up to 52% of individuals (again at the 15 mg dosage) obtained a level below 5.7%, while almost 80% of participants receiving 15 mg of Mounjaro achieved goal HbA1c values of 6.5% or below. Within 40 weeks, those who took Mounjaro lost about 15 to 21 pounds, and higher doses yielded better results. 

How To Decide Which Is Best: Zepbound or Mounjaro?  

If you are searching for: what is Zepbound vs Mounjaro? Which one would be better for you? Then, both are safe and efficient treatment options. A healthcare expert can assist you in selecting the best one for you.  

You might be able to evaluate if it is cheaper to take medication and if the insurance will indeed pay for it. This is because prescription medicines taken for qualified use tend to be reimbursable by insurance. In cases where a patient suffers from obesity or is overweight and has a non-diabetes-related health condition, then Zepbound is useful for the long-term weight management journey, and Mounjaro is good for managing type 2 diabetes.  

Other things would include your tolerance for negative effects. Zepbound has a somewhat longer list of normal side effects; those are more common than those listed above – belching, hair loss, dizziness, and suicidal behavior. It might be helpful to talk about these side effects with your healthcare physician, even if they are still quite infrequent. 

To Sum Up… 

Both Zepbound and Mounjaro use the chemical tirzepatide. However, Eli Lily has been marketing Mounjaro as a type 2 diabetic medication. Zepbound is useful as a remedy for people wishing to lose weight. It is important to learn what is Zepbound vs Mounjaro, so you can make a proper choice and come to the right decision about which medicine to take.  At Direct Preventive Care, we help treat type 2 diabetes through personalized therapy by understanding the root cause of the disease and its symptoms and curing it.  Before you take a step in considering these two medicines, book a consultation or visit us to discuss them with our experts.