What Is Zepbound vs Mounjaro? 

What Is Zepbound vs Mounjaro?  If you have type 2 diabetes and wish to keep it under control or wish to shed some weight, your physician may have recommended Mounjaro or Zepbound. The producers of these two drugs are Eli Lilly, and both have tendencies to cause diarrhea, nausea, and vomiting; their active component is tirzepatide. Let’s discuss in detail: What is Zepbound vs Mounjaro?  Key Difference Between Zepbound and Mounjaro  In the UK, the medicine goes by the name “Mounjaro” and is useful in diabetes and the management of Obesity. However, in the US, the same compound is marketed as ‘’Zepbound” for managing obesity and ‘’Mounjaro” for type 2 diabetes.   The generic names of tirzepatide include Zepbound and Mounjaro. This is aimed at the glucagon-like peptide-1, GLP-1, a hormone branded in the dual role of a glucose and hunger regulator. These medications function in this way: they resemble GLP-1, and they regulate blood sugar, hunger, and feeding, which causes diabetic people to lose weight. Tirzepatide is marketed in the US as well as in other parts of the world for weight loss under the name “Zepbound” and for diabetes treatment as “Mounjaro.”   The FDA has authorized Zepbound and Mounjaro to treat different medical conditions; Zepbound addresses weight loss, while Mounjaro cures type 2 diabetes. Continue reading to learn the meaning of What is Zepbound vs Mounjaro? their differences and similarities.   Active Ingredients  The active component of Zepbound and Mounjaro is tirzepatide. Tirzepatide’s physiological effects are imitated by two endogenous hormones: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1).   GLP-1 slows down digestion by making food move from your stomach to your intestine more slowly after you eat, a process known as gastric emptying. Simultaneously, it increases insulin release and decreases glucagon release. GIP amplifies these effects of glucagon inhibition and insulin stimulation, improving fat burning in your body. These two actions work together to help reduce blood sugar levels and make you feel fuller sooner. You could eat less as a result and shed some pounds.  More research suggests that GLP-1 and GIP have an impact on your brain, which may influence your appetite and feel full. When Mounjaro initially came on the market, it was the first medication of its kind to target both GIP and GLP receptors. This sets it apart from other injectable drugs for weight reduction or type 2 diabetes, including Wegovy or Ozempic, which exclusively target the GLP-1 receptor.   Side Effects  The list of gastrointestinal side effects for Zepbound and Mounjaro is comparable and often falls into the mild to severe category. Typical adverse effects include:  Other potential side effects of Zepbound include injection site reactions (bruising, redness, or irritation at the injection site), fatigue, allergic reactions (typically rash and itching), belching, hair loss, and acid reflux.  Overcome Effects of Zepbound or Mounjaro  Thus, if it is appropriate, your healthcare provider will allow you to consume either Zepbound or Mounjaro after considering your family’s medical history and a list of prescription drugs and vitamin supplements you take. The usual digestive adverse effects of these medications may be lessened by taking them as per directions. Likewise, dietary modifications like:  Which Works Better: Zepbound or Mounjaro?   Zepbound and Mounzaro can be very helpful for people with type 2 diabetes, obesity, or overweight when used together. After about a year and a half, individuals with obesity who were not diabetic lost an average of 15% to 21% of their body weight. In addition to losing weight, the participants saw noteworthy improvements in other aspects of their cardiometabolic health, including:  Moreover, almost 95% of patients who started the trial with prediabetes achieved normal blood sugar levels by the end of the investigation.  In a type 2 diabetes clinical trial, Mounjaro reduced hemoglobin A1c (HbA1c) levels on average by 1.87% to 2.07%. Up to 52% of individuals (again at the 15 mg dosage) obtained a level below 5.7%, while almost 80% of participants receiving 15 mg of Mounjaro achieved goal HbA1c values of 6.5% or below. Within 40 weeks, those who took Mounjaro lost about 15 to 21 pounds, and higher doses yielded better results.  How To Decide Which Is Best: Zepbound or Mounjaro?   If you are searching for: what is Zepbound vs Mounjaro? Which one would be better for you? Then, both are safe and efficient treatment options. A healthcare expert can assist you in selecting the best one for you.   You might be able to evaluate if it is cheaper to take medication and if the insurance will indeed pay for it. This is because prescription medicines taken for qualified use tend to be reimbursable by insurance. In cases where a patient suffers from obesity or is overweight and has a non-diabetes-related health condition, then Zepbound is useful for the long-term weight management journey, and Mounjaro is good for managing type 2 diabetes.   Other things would include your tolerance for negative effects. Zepbound has a somewhat longer list of normal side effects; those are more common than those listed above – belching, hair loss, dizziness, and suicidal behavior. It might be helpful to talk about these side effects with your healthcare physician, even if they are still quite infrequent.  To Sum Up…  Both Zepbound and Mounjaro use the chemical tirzepatide. However, Eli Lily has been marketing Mounjaro as a type 2 diabetic medication. Zepbound is useful as a remedy for people wishing to lose weight. It is important to learn what is Zepbound vs Mounjaro, so you can make a proper choice and come to the right decision about which medicine to take.  At Direct Preventive Care, we help treat type 2 diabetes through personalized therapy by understanding the root cause of the disease and its symptoms and curing it.  Before you take a step in considering these two medicines, book a consultation or visit us to discuss them with our experts. 

Is Collagen Safe For Fatty Liver? 

Your liver is only as strong as the amount of collagen in it, which makes it an arduous detoxifier and metabolic powerhouse known as hepatocytes. This is essential to keeping livers in good condition and avoiding cirrhosis or hepatic fibrosis. Collagen is connective tissue that keeps the liver healthy, including hepatocytes, structurally intact, and helps ward off cirrhosis and fibrosis of the liver. In this blog post, we will discuss – is collagen safe for fatty liver?  Can a Fatty Liver Benefit from Collagen?  Fat liver diseases such as non-alcoholic fatty liver disease (NAFLD) and its more severe variant, non-alcoholic steatohepatitis (NASH), are becoming more prevalent in the population. It may cause liver cancer, fibrosis, and cirrhosis, among other dangerous adverse effects.  Recent research has demonstrated that the amino acid glycine, which is present in collagen, protects the liver. Many people wonder, is collagen safe for fatty liver? The answer appears to be yes, as glycine in collagen has shown potential benefits for liver health.  Lower Glycine Levels in NAFLD:  Glycine levels in the blood are frequently decreased in NAFLD patients. Increased risks of obesity, type 2 diabetes, and cardiovascular illnesses are associated with this deficit.  Results of the Clinical Study:  According to a 2020 study conducted by the Michigan Medicine Frankel Cardiovascular Centre, glycine, either by itself or in combination with leucine, can aid in the prevention and treatment of obesity-related fatty liver disease.  Glycine levels are consistently lower in patients with non-alcoholic fatty liver disease (NAFLD) and associated comorbidities. According to the study, glycine at a daily dose of 27 mg/kg, or around 2 g per day, may have therapeutic benefits. One 10g dosage of CollagenX hydrolyzed collagen has this quantity.  Can Collagen Help With Cirrhosis of the Liver?  A severe illness known as liver cirrhosis causes the liver to become scarred and lose its ability to function. Even though severe cirrhosis is difficult to cure, the condition is manageable.  The Function of Glycine:   Hydrolyzed collagen contains a lot of glycine, which has anti-inflammatory and antioxidant qualities that can help maintain liver function.  Research Findings:   The same 2020 study also discovered that leucine, which is also present in hydrolyzed collagen, and glycine worked better together to reverse inflammation and liver damage than glycine alone.  By incorporating hydrolyzed collagen into your diet, you may support liver function and maybe decrease the onset of cirrhosis by maintaining appropriate levels of leucine and glycine.  How to Prevent Non-Alcoholic Fatty Liver Disease?  A comprehensive strategy can prevent NAFLD. This requires eating a balanced diet, exercising often, and keeping a healthy weight. This is how collagen functions in this context:  Healthy Weight:   Maintaining a healthy weight can reduce the risk of NAFLD. Exercise and a balanced diet can help. Hydrolyzed collagen contains leucine and glycine, which promote metabolic health and may help with weight management.  A Well-Rounded Diet:  Include foods high in glycine, such as spinach, meats, dairy, beans, and shellfish. Although, For optimum health, these sources may not offer enough glycine, though.  Daily Exercise:   Exercise enhances liver function and aids in maintaining a healthy weight. These advantages can be increased by combining collagen supplements with exercise.  Supplementing With Collagen:   Ensuring sufficient intake of glycine and leucine promotes liver function and general metabolism. Dietary Collagen: The Secret Power of the Liver  Dietary collagen may lessen the incidence of cirrhosis and fibrogenesis by preventing fat from accumulating in hepatocytes, the cells that make up the liver.  Medicine facilitates liver cleansing by lowering inflammation and boosting healthy tissue. Macrophages’ interaction with cells is a part of this process.  Collagen’s Function in NAFLD and ALD  A distinct contrast is visible when we look at patient cells under a microscope that have both liver cirrhosis and inflammation. Collagen synthesis is affected in cases of both ALD and NAFLD. These disorders are frequently associated with chronic liver disease, which may result in liver fibrosis or even liver cirrhosis. This progression of fibrosis is concerning. It seems like your liver is trying to fight fibrosis and inflammation by making more collagen. But it ends up overproducing, which causes fibrotic cells.  Overproduction of collagen causes inflammation and fibrotic alterations in cells, which results in the condition known as fibrosis, or scarring of the liver tissue. Think of your cells creating fibrosis and inflammation, akin to a skin scar following an accident.   Collagen Role in Maintaining Liver Health   Here are some more details about – is collagen safe for fatty liver. T1rho imaging reveals that collagen, which is essential to the structure of cells, is involved in preserving liver function and preventing fibrosis. T1rho promotes overall healthy liver function, helps prevent fibrosis (scarring), and repairs damaged hepatocytes (liver cells).  Incorporate Collagen Into Diet  Foods like bone broth, fish and chicken skin, and some meat cuts naturally contain collagen This is vital for cells and the control of liver fibrosis. These resources could help keep liver levels stable. As an alternative, you can nourish cells and perhaps help manage liver fibrosis and liver T1rho by using supplements like collagen powders or capsules.  Is Collagen Safe For Liver: Side Effects Of Consuming Excessive Collagen  Collagen is considered safe and has few side effects when liver fibrosis and liver T1rho are present. However, a small number of individuals may experience mild gastrointestinal issues or allergic reactions linked to liver fibrosis, liver collagen, and liver T1rho. As always, you should see a physician before starting a new supplement regimen, especially if you have T1rho or liver fibrosis.  Final Words  The epidemic known as non-alcoholic fatty liver disease (NAFLD) presently has no approved medicinal treatments. Hydrolyzed collagen contains glycine, which is a potentially useful natural method for supporting liver function. Maintaining a healthy weight, getting regular exercise, eating a balanced diet, and taking collagen supplements can all help to preserve your liver. To find the solution to the question – is collagen safe for fatty liver, book a consultation with Direct Preventive Care for a personalized treatment plan to take control of your liver’s health.

Which Supplement Is Good For Balancing Hormones? 

Which Supplement Is Good For Balancing Hormones? Hormone health has gathered a lot of attention in the functional wellness movement, which is a worthy cause. The hormones significantly affect all body systems, including metabolism, adrenals, and fertility. When hormones change, it results in the emergence of certain conditions, including fatigue, weight gain, and sleep disturbance. Gladly, the structure that maintains hormonal balance can be achieved by a healthy diet, exercise, stress management, and supplementation. In this blog, we are going to discuss which supplement is nourishing for the body and, most importantly, which supplement is good for balancing hormones.  Using Supplements to Balance Hormones  Hormonal changes in the female body might lead to a loss of balance in key hormones; thus, there is a need to seek supplements for balance. Hormones that play crucial roles in women’s menstrual cycles, sexual function, and reproductive health include:  Estrogen: Controls menstrual cycle and also stimulates the secretion of progesterone and estrogen. Progesterone: Similar to estrogen, it has an impact on the menstrual cycle and fertility due to its actions.  Testosterone: It is involved in the regulation of sexual activity, bone health, and muscle power.  Follicle Stimulating Hormone (FSH): Influences the synthesis of estradiol and ovaries, menstrual cycle, and oocyte production.  Cortisol: It is the stress hormone that affects the pulse rate, blood pressure, gut function, and sexual activity.  Which Supplement Is Good For Balancing Hormones? Here is the list of supplements  for balancing hormones:  1. B Vitamins  B vitamins are in a special category because they perform critical functions during the manufacture of hormones and the maintenance of hormonal balance. They help in the carrying out of liver detoxification processes, which are very important in neutralizing and eliminating damaging products such as hormone metabolites from the body. This process depends on sufficient amounts of folate, vitamin B12, and vitamin B6. For instance, some estrogen metabolites are genotoxic, and this methylation counteracts the effect and allows the safe elimination of the metabolites.  Which supplement is good for balancing hormones? One of them is B vitamins which are necessary for normal metabolism and hormonal activity of the gland. There are certain diseases that are sometimes associated with the deficiency of B12 and B6, such as hypothyroidism and diabetes. In particular, these vitamins are important for blood sugar control, with the help of insulin and glucagon, which are metabolic hormones. B6 has also been widely researched when it comes to the treatment of PMS differently and successfully demonstrated its ability to cure symptoms such as bloating, mood swings, and anxiety.  2. Probiotics  The gut bacteria have the responsibility of maintaining the hormonal balance in the human body. Stress-inducing cortisol hormone may affect motility and barrier properties of the gut; estrogen levels to reduced, and the permeability to endotoxin and inflammation increase. However, the dependency is two-way, and on this front, the gut microbiome affects hormone health.  Probiotics may favor the synthesis of short-chain fatty acids, which can influence the levels of energy, glucose use, fat, and inflammation. They also act on intimate hormones and are beneficial for PCOS, infertility, and excessive estrogen levels.   3. Zinc  To answer which supplement is good for balancing hormones- consider zinc as a major role player. Zinc plays a vital role in the proper functioning of the hormones, such as thyroid hormones and insulin. It is very important in the functioning of intimate hormones necessary for ovulation and pregnancy. Zinc affects the levels of testosterone in women. It is helpful in treating PCOS since it lowers the level of androgens.  4. Omega-3 Fatty Acids  Omega-3s are anti-inflammatory and are vital for hormone balance, according to researchers. They can control the level of the luteinizing hormone in women with PCOS and testosterone, sex hormone-binding globulin, as well as enhance insulin sensitivity. Omega-3 is also useful to post-menopausal women as it raises estrogen levels and acts as a barrier to bone loss.  5. Vitamin D3  Vitamin D is a steroid hormone present in almost all body tissues. It plays an important role in the synthesis of bones, positive regulation of bone mineralization, and insulin action. They aid in regulating estrogen and progestin. Lack of vitamin D results in osteoporosis, and taking it will improve the metabolism of insulin.  6. Rhodiola  Rhodiola is an adaptogen that may help decrease the extent to which chronic stress impacts the body and, additionally and more significantly, help regulate cortisol stress hormones produced by the adrenal glands. It enhances cognitive function and fights fatigue, mostly under conditions of chronic stress.  7. Red Raspberry Leaf  Sometimes, red raspberry is used as a galactosemic that tones the muscles of the female uterus. It raises blood flow in the pelvis, relieves menstrual pain, and has calcium, iron, potassium, and vitamins A, C, and E. 8. Chasteberry (Vitex)  Chasteberry is useful for female health and hormonal support. It influences the secretion of the pituitary gland in decreasing prolactin and increasing the luteinizing hormone essential in the synthesis of progesterone. Research also proves that chasteberry substantially reduces the common symptoms of PMS and menopausal issues, including anxiety and hot flashes.   Lifestyle modifications to support Hormonal     When thinking about which supplement is good for balancing hormones, there are plenty in the market. Besides supplementation, a change of lifestyle is mandatory to influence hormone levels. Reducing the proportion of ultra-processed foods by replacing them with vegetables, fruits, nuts, seeds, and legumes makes for a higher fiber intake. It nourishes the beneficial gut bacteria that maintain hormonal balance. Probiotic foods like yogurt, kefir, sauerkraut, miso, and kimchi can improve the content of the beneficial bacteria in the gut. Fiber also assists in keeping blood sugar levels stable or low. This is because fiber has the capacity to slow down the absorption of sugars.  Cruciferous vegetables that include broccoli, kale and Brussels sprouts have estrogen-suppressing effects. They also reduce the creation of toxic estrogen metabolites.    Key Takeaways    Regulating hormones is essential and central to the overall health of an individual. Healthy food, regular exercise, how to manage stress and proper supplementation would assist the hormones in